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Increased Calcific Aortic Valve Disease in response to a diabetogenic, procalcific diet in the LDLr(−/−)ApoB(100/100) mouse model
OBJECTIVE: Calcific aortic valve disease (CAVD) is a major cause of aortic stenosis (AS) and cardiac insufficiency. Patients with type II diabetes mellitus (T2DM) are at heightened risk for CAVD, and their valves have greater calcification than nondiabetic valves. No drugs to prevent or treat CAVD e...
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| Publicado no: | Cardiovasc Pathol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940574/ https://ncbi.nlm.nih.gov/pubmed/29539583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2018.02.002 |
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