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Clinical characteristics of non-small cell lung cancer harboring mutations in exon 20 of EGFR or HER2

Unlike common epidermal growth factor receptor gene (EGFR) mutations that confer sensitivity to tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC), mutations in exon 20 of either EGFR or the human EGFR2 gene (HER2) are associated with insensitivity to EGFR-TKIs, with treatment o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Takeda, Masayuki, Sakai, Kazuko, Hayashi, Hidetoshi, Tanaka, Kaoru, Tanizaki, Junko, Takahama, Takayuki, Haratani, Koji, Nishio, Kazuto, Nakagawa, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940408/
https://ncbi.nlm.nih.gov/pubmed/29765525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24958
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