Selective dissociation between LSD1 and GFI1B by a LSD1 inhibitor NCD38 induces the activation of ERG super-enhancer in erythroleukemia cells

Lysine-specific demethylase 1 (LSD1) is a histone modifier for transcriptional repression involved in the regulation of hematopoiesis. We previously reported that a LSD1 inhibitor NCD38 induces transdifferentiation from erythroid lineage to granulomonocytic lineage and exerts anti-leukemia effect th...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Yamamoto, Ryusuke, Kawahara, Masahiro, Ito, Shinji, Satoh, Junko, Tatsumi, Goichi, Hishizawa, Masakatsu, Suzuki, Takayoshi, Andoh, Akira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2018
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940392/
https://ncbi.nlm.nih.gov/pubmed/29765516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24774
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items