Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response

Maintenance of genomic integrity is crucial for the preservation of hematopoietic stem cell (HSC) potential. Retrotransposons, spreading in the genome through an RNA intermediate, have been associated with loss of self-renewal, aging, and DNA damage. However, their role in HSCs has not been addresse...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Barbieri, Daniela, Elvira-Matelot, Emilie, Pelinski, Yanis, Genève, Laetitia, de Laval, Bérengère, Yogarajah, Gayathri, Pecquet, Christian, Constantinescu, Stefan N., Porteu, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940259/
https://ncbi.nlm.nih.gov/pubmed/29615469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170997
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados