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A net-shaped multicellular formation facilitates the maturation of hPSC-derived cardiomyocytes through mechanical and electrophysiological stimuli

The use of human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is limited in drug discovery and cardiac disease mechanism studies due to cell immaturity. Although many approaches have been reported to improve the maturation of hiPSC-CMs, the elucidation of the process of maturatio...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Liu, Taoyan, Huang, Chengwu, Li, Hongxia, Wu, Fujian, Luo, Jianwen, Lu, Wenjing, Lan, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940117/
https://ncbi.nlm.nih.gov/pubmed/29661985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101411
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