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The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: possible relevance for treatment-resistant depression

Major depression is a highly complex disabling psychiatric disorder affecting millions of people worldwide. Despite the availability of several classes of antidepressants, a substantial percentage of patients are unresponsive to these medications. A better understanding of the neurobiology of depres...

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Vydáno v:Neuropharmacology
Hlavní autoři: Meylan, Elsa M., Halfon, Olivier, Magistretti, Pierre J., Cardinaux, Jean-René
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939991/
https://ncbi.nlm.nih.gov/pubmed/26970016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.03.012
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