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The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: possible relevance for treatment-resistant depression
Major depression is a highly complex disabling psychiatric disorder affecting millions of people worldwide. Despite the availability of several classes of antidepressants, a substantial percentage of patients are unresponsive to these medications. A better understanding of the neurobiology of depres...
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Publicado no: | Neuropharmacology |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5939991/ https://ncbi.nlm.nih.gov/pubmed/26970016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.03.012 |
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