A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage

A lack of analytically robust and multiplexed assays has hampered studies of the large, branched phosphosignaling network responsive to DNA damage. To address this need, we developed and fully analytically characterized a 62-plex assay quantifying protein expression and post-translational modificati...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Whiteaker, Jeffrey R., Zhao, Lei, Saul, Rick, Kaczmarczyk, Jan A., Schoenherr, Regine M., Moore, Heather D., Jones-Weinert, Corey, Ivey, Richard G., Lin, Chenwei, Hiltke, Tara, Reding, Kerryn W., Whiteley, Gordon, Wang, Pei, Paulovich, Amanda G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939939/
https://ncbi.nlm.nih.gov/pubmed/29474155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14963.1
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