Efficacy of opioids versus placebo in chronic pain: a systematic review and meta-analysis of enriched enrollment randomized withdrawal trials

INTRODUCTION: Opioids have been used for millennia for the treatment of pain. However, the long-term efficacy of opioids to treat chronic non-cancer pain continues to be debated. To evaluate opioids’ efficacy in chronic non-cancer pain, we performed a meta-analysis of published clinical trials for μ...

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Опубликовано в: :J Pain Res
Главные авторы: Meske, Diana S, Lawal, Oluwadolapo D, Elder, Harrison, Langberg, Valerie, Paillard, Florence, Katz, Nathaniel
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2018
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939920/
https://ncbi.nlm.nih.gov/pubmed/29765246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S160255
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