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The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases

BACKGROUND: Cryptosporidiosis affects all human populations, but can be much more severe or life-threatening in children and individuals with weak or weakened immune systems. However, current options to treat cryptosporidiosis are limited. METHODS: An in vitro phenotypic screening assay was employed...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Guo, Fengguang, Zhang, Haili, McNair, Nina N, Mead, Jan R, Zhu, Guan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939870/
https://ncbi.nlm.nih.gov/pubmed/29300993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix689
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