Diminished Capsule Exacerbates Virulence, Blood–Brain Barrier Penetration, Intracellular Persistence, and Antibiotic Evasion of Hyperhemolytic Group B Streptococci

Group B streptococci (GBS) are encapsulated, β-hemolytic bacteria that are a common cause of infections in human newborns and certain adults. Two factors important for GBS virulence are the sialic acid capsular polysaccharide that promotes immune evasion and the hemolytic pigment that induces host c...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Gendrin, Claire, Merillat, Sean, Vornhagen, Jay, Coleman, Michelle, Armistead, Blair, Ngo, Lisa, Aggarwal, Anjali, Quach, Phoenicia, Berrigan, Jacob, Rajagopal, Lakshmi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939829/
https://ncbi.nlm.nih.gov/pubmed/29301010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix684
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