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Investigator‐initiated randomized controlled trials in children with epilepsy: Mission impossible?

OBJECTIVE: In children many antiepileptic drugs (AEDs) are prescribed off‐label due to a lack of well‐designed randomized controlled trials (RCTs). We conducted a multicenter RCT in the Netherlands to compare levetiracetam and valproic acid as monotherapy in children with newly diagnosed epilepsy. A...

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Udgivet i:Epilepsia Open
Main Authors: Weijenberg, Amerins, Callenbach, Petra M. C., Brouwer, Oebele F.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939385/
https://ncbi.nlm.nih.gov/pubmed/29750211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/epi4.12024
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