Programmed cell death 5 suppresses AKT-mediated cytoprotection of endothelium

Programmed cell death 5 (PDCD5) has been associated with human cancers as a regulator of cell death; however, the role of PDCD5 in the endothelium has not been revealed. Thus, we investigated whether PDCD5 regulates protein kinase B (PKB/AKT)-endothelial nitric oxide synthase (eNOS)–dependent signal...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lee, Seung-Hyun, Seo, Jaesung, Park, Soo-Yeon, Jeong, Mi-Hyeon, Choi, Hyo-Kyoung, Lee, Chan Joo, Kim, Mi Jeong, Guk, Garam, Lee, SooYeon, Park, Hyewon, Jeong, Jae-Wook, Ha, Chang Hoon, Park, Sungha, Yoon, Ho-Geun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939060/
https://ncbi.nlm.nih.gov/pubmed/29588416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712918115
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