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WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia
Liver cancer is one of the most lethal malignancies with very poor prognosis once diagnosed. The most common form of liver cancer is hepatocellular carcinoma (HCC). The WW domain-containing oxidoreductase (WWOX) is a large gene that is often perturbed in a wide variety of tumors, including HCC. WWOX...
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| Pubblicato in: | Cell Death Dis |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5938702/ https://ncbi.nlm.nih.gov/pubmed/29724996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0510-4 |
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