A trial like ALIC(4)E: why design a platform, response-adaptive, open, randomised controlled trial of antivirals for influenza-like illness?

ALIC(4)E is the first publicly funded, multicountry, pragmatic study determining whether antivirals should be routinely prescribed for influenza-like illness in primary care. The trial aims to go beyond determining the average treatment effect in a population to determining effects in patients with...

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Bibliografische gegevens
Gepubliceerd in:ERJ Open Res
Hoofdauteurs: Butler, Christopher C., Coenen, Samuel, Saville, Benjamin R., Cook, Johanna, van der Velden, Alike, Homes, Jane, de Jong, Menno, Little, Paul, Goossens, Herman, Beutels, Philippe, Ieven, Margareta, Francis, Nick, Moons, Pieter, Bongard, Emily, Verheij, Theo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: European Respiratory Society 2018
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Perspective
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938489/
https://ncbi.nlm.nih.gov/pubmed/29761108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00046-2018
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