Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice

Mechanisms of pain resolution are largely unclear. Increasing evidence suggests that specialized pro-resolving mediators (SPMs), derived from fish oil docosahexaenoic acid (DHA), promote the resolution of acute inflammation and potently inhibit inflammatory and neuropathic pain. In this study, we ex...

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Vydáno v:Front Pharmacol
Hlavní autoři: Zhang, Linlin, Terrando, Niccolò, Xu, Zhen-Zhong, Bang, Sangsu, Jordt, Sven-Eric, Maixner, William, Serhan, Charles N., Ji, Ru-Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938385/
https://ncbi.nlm.nih.gov/pubmed/29765320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00412
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