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Increased Piezo1 channel activity in interstitial Cajal-like cells induces bladder hyperactivity by functionally interacting with NCX1 in rats with cyclophosphamide-induced cystitis

The Piezo1 channel is a mechanotransduction mediator, and Piezo1 abnormalities have been linked to several clinical disorders. However, the role of the Piezo1 channel in cystitis-associated bladder dysfunction has not been documented. The current study aimed to discover the functional role of this c...

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Detalles Bibliográficos
Publicado en:Exp Mol Med
Main Authors: Liu, Qian, Sun, Bishao, Zhao, Jiang, Wang, Qingqing, An, Fan, Hu, Xiaoyan, Yang, Zhenxing, Xu, Jie, Tan, Mingjia, Li, Longkun
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938236/
https://ncbi.nlm.nih.gov/pubmed/29735991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0088-z
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