Exosomes from adipose-derived stem cells overexpressing Nrf2 accelerate cutaneous wound healing by promoting vascularization in a diabetic foot ulcer rat model

Diabetic foot ulcers (DFU) increase the risks of infection and amputation in patients with diabetes mellitus (DM). The impaired function and senescence of endothelial progenitor cells (EPCs) and high glucose-induced ROS likely exacerbate DFUs. We assessed EPCs in 60 patients with DM in a hospital or...

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Veröffentlicht in:Exp Mol Med
Hauptverfasser: Li, Xue, Xie, Xiaoyun, Lian, Weishuai, Shi, Rongfeng, Han, Shilong, Zhang, Haijun, Lu, Ligong, Li, Maoquan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938041/
https://ncbi.nlm.nih.gov/pubmed/29651102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0058-5
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