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Role of phospholipase D in the lifespan of Caenorhabditis elegans

We have previously shown that phospholipase D (PLD) downregulation accelerates cellular senescence, which is widely believed to play an important role in aging, by stimulating reactive oxygen species (ROS) accumulation in human cells. In this study, we examined the role of PLD in aging using the nem...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Park, Jeong-Hwan, Park, Jeong-Woo, Lee, Ju-Hyeon, Kim, Dong-Yun, Hahm, Jeong-Hoon, Bae, Young-Seuk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938010/
https://ncbi.nlm.nih.gov/pubmed/29622768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-017-0015-8
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