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Highly elevated soluble Tim-3 levels correlate with increased hepatocellular carcinoma risk and poor survival of hepatocellular carcinoma patients in chronic hepatitis B virus infection
BACKGROUND AND OBJECTIVE: Upregulated T-cell immunoglobulin and mucin domain containing molecule-3 (Tim-3) in hepatitis B virus (HBV)-specific CD8(+) T-cells contributes to CD8(+) T-cell exhaustion during chronic HBV infection. The membrane-bound Tim-3 can be cleaved from the cell surface by sheddas...
Gardado en:
| Publicado en: | Cancer Manag Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Dove Medical Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937498/ https://ncbi.nlm.nih.gov/pubmed/29760564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S162478 |
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