MiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells

BACKGROUND: hTERT gene plays an important role in melanoma, although the specific mechanism involved is unclear. The aim of this study was to screen and identify the relative miRNAs with the regulation of hTERT in melanoma. MATERIALS AND METHODS: Quantitative real-time polymerase chain reaction (q-P...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Chai, Li, Kang, Xiao-Jing, Sun, Zhen-Zhu, Zeng, Ming-Feng, Yu, Shi-Rong, Ding, Yuan, Liang, Jun-Qin, Li, Ting-Ting, Zhao, Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937487/
https://ncbi.nlm.nih.gov/pubmed/29760567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S163335
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