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A Critical Role for Dna2 at Unwound Telomeres
Dna2 is a nuclease and helicase that functions redundantly with other proteins in Okazaki fragment processing, double-strand break resection, and checkpoint kinase activation. Dna2 is an essential enzyme, required for yeast and mammalian cell viability. Here, we report that numerous mutations affect...
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Publicado no: | Genetics |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Genetics Society of America
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937186/ https://ncbi.nlm.nih.gov/pubmed/29559500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300809 |
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