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A Critical Role for Dna2 at Unwound Telomeres

Dna2 is a nuclease and helicase that functions redundantly with other proteins in Okazaki fragment processing, double-strand break resection, and checkpoint kinase activation. Dna2 is an essential enzyme, required for yeast and mammalian cell viability. Here, we report that numerous mutations affect...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Markiewicz-Potoczny, Marta, Lisby, Michael, Lydall, David
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937186/
https://ncbi.nlm.nih.gov/pubmed/29559500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300809
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