Use of functional respiratory imaging to characterize the effect of inhalation profile and particle size on lung deposition of inhaled corticosteroid/long-acting β2-agonists delivered via a pressurized metered-dose inhaler

BACKGROUND: Functional respiratory imaging (FRI) uses three-dimensional models of human lungs and computational fluid dynamics to simulate functional changes within airways and predict the deposition of inhaled drugs. This study used FRI to model the effects of different patient inhalation and drug...

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Publicat a:Ther Adv Respir Dis
Autors principals: Van Holsbeke, Cedric, De Backer, Jan, Vos, Wim, Marshall, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937159/
https://ncbi.nlm.nih.gov/pubmed/29499614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753466618760948
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