Synergism of Antimicrobial Frog Peptides Couples to Membrane Intrinsic Curvature Strain

Mixtures of the frog peptides magainin 2 and PGLa are well-known for their pronounced synergistic killing of Gram-negative bacteria. We aimed to gain insight into the underlying biophysical mechanism by interrogating the permeabilizing efficacies of the peptides as a function of stored membrane curv...

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Bibliografiska uppgifter
I publikationen:Biophys J
Huvudupphovsmän: Leber, Regina, Pachler, Michael, Kabelka, Ivo, Svoboda, Irene, Enkoller, Daniel, Vácha, Robert, Lohner, Karl, Pabst, Georg
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2018
Ämnen:
Membranes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937145/
https://ncbi.nlm.nih.gov/pubmed/29694871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.006
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