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Preferential cytotoxicity of the type I ribosome inactivating protein alpha-momorcharin on human nasopharyngeal carcinoma cells under normoxia and hypoxia

All primary nasopharyngeal carcinoma (NPC) tumors contain hypoxic regions which are implicated in decreased local control and increased distant metastases, as well as resistance to chemotherapy in advanced NPC patients. One of the promising therapeutic approaches for NPC is to use drugs that can tar...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Pan, Wen Liang, Wong, Jack Ho, Fang, Evandro Fei, Chan, Yau Sang, Ng, Tzi Bun, Cheung, Randy Chi Fai
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937121/
https://ncbi.nlm.nih.gov/pubmed/24637239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.03.004
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