Design, Synthesis and Biological Evaluation of Novel Peptide-Like Analogues as Selective COX-2 Inhibitors

A new series of peptide-like derivatives containing different aromatic amino acids and possessing pharmacophores of COX-2 inhibitors as SO(2)Me or N(3 )attached to the para position of an end phenyl ring was synthesized for evaluation as selective cyclooxygenase-2 (COX-2) inhibitors. The synthetic r...

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Veröffentlicht in:Iran J Pharm Res
Hauptverfasser: Ahmaditaba, Mohammad Ali, Houshdar Tehrani, Mohammad Hassan, Zarghi, Afshin, Shahosseini, Sorayya, Daraei, Bahram
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shaheed Beheshti University of Medical Sciences 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937080/
https://ncbi.nlm.nih.gov/pubmed/29755541
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