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Preclinical Study of Ibuprofen Loaded Transnasal Mucoadhesive Microemulsion for Neuroprotective Effect in MPTP Mice Model

Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), showed very promising neuroprotection action, but it suffers from high first pass metabolism and limited ability to cross blood brain barrier. Severe gastric toxicity following oral administration further limits its utility. Hence, the aim o...

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Bibliografische gegevens
Gepubliceerd in:Iran J Pharm Res
Hoofdauteurs: Mandal, Surjyanarayan, Mandal, Snigdha Das, Chuttani, Krishna, Sawant, Krutika K, Subudhi, Bharat Bhushan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Shaheed Beheshti University of Medical Sciences 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937075/
https://ncbi.nlm.nih.gov/pubmed/29755536
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