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Dissemination of Orientia tsutsugamushi, a Causative Agent of Scrub Typhus, and Immunological Responses in the Humanized DRAGA Mouse

Scrub typhus is caused by Orientia tsutsugamushi, an obligated intracellular bacterium that affects over one million people per year. Several mouse models have been used to study its pathogenesis, disease immunology, and for testing vaccine candidates. However, due to the intrinsic differences betwe...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Jiang, Le, Morris, Erin K., Aguilera-Olvera, Rodrigo, Zhang, Zhiwen, Chan, Teik-Chye, Shashikumar, Soumya, Chao, Chien-Chung, Casares, Sofia A., Ching, Wei-Mei
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936984/
https://ncbi.nlm.nih.gov/pubmed/29760694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00816
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