Multiplexed Nanopore Sequencing of HLA-B Locus in Māori and Pacific Island Samples

The human leukocyte antigen (HLA) system encodes the human major histocompatibility complex (MHC). HLA-B is the most polymorphic gene in the MHC class I region and many HLA-B alleles have been associated with adverse drug reactions (ADRs) and disease susceptibility. The frequency of such HLA-B allel...

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Bibliographic Details
Published in:Front Genet
Main Authors: Ton, Kim N. T., Cree, Simone L., Gronert-Sum, Sabine J., Merriman, Tony R., Stamp, Lisa K., Kennedy, Martin A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936980/
https://ncbi.nlm.nih.gov/pubmed/29760718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00152
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