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Disruption in Thyroid Signaling Pathway: A Mechanism for the Effect of Endocrine-Disrupting Chemicals on Child Neurodevelopment

Thyroid hormones are crucial in normal brain development. Transient and mild thyroid hormone insufficiency in pregnancy is also associated with impaired neurodevelopment in the offspring (e.g., 3–4 IQ score loss in association with maternal free thyroxine in the lowest fifth percentile). While inade...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Ghassabian, Akhgar, Trasande, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936967/
https://ncbi.nlm.nih.gov/pubmed/29760680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00204
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