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Disruption in Thyroid Signaling Pathway: A Mechanism for the Effect of Endocrine-Disrupting Chemicals on Child Neurodevelopment

Thyroid hormones are crucial in normal brain development. Transient and mild thyroid hormone insufficiency in pregnancy is also associated with impaired neurodevelopment in the offspring (e.g., 3–4 IQ score loss in association with maternal free thyroxine in the lowest fifth percentile). While inade...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autoři: Ghassabian, Akhgar, Trasande, Leonardo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936967/
https://ncbi.nlm.nih.gov/pubmed/29760680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00204
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