Ophiopogonin D′, a Natural Product From Radix Ophiopogonis, Induces in Vitro and in Vivo RIPK1-Dependent and Caspase-Independent Apoptotic Death in Androgen-Independent Human Prostate Cancer Cells

Objective: The purpose of this study was to evaluate the anticancer effects of Ophiopogonin D′ (OPD′, a natural product extracted from a traditional Chinese medicine (Radix Ophiopogonis) against androgen-independent prostate cancer cells and to explore the underlying molecular mechanism(s) of action...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lu, Zongliang, Wang, He, Zhu, Mingxing, Song, Wei, Wang, Jiajia, Wu, Changpeng, Kong, Ya, Guo, Jing, Li, Na, Liu, Jie, Li, Yanwu, Xu, Hongxia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936779/
https://ncbi.nlm.nih.gov/pubmed/29760660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00432
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