Protein Kinase Serine/Threonine Kinase 24 Positively Regulates Interleukin 17-Induced Inflammation by Promoting IKK Complex Activation

Interleukin 17 (IL-17) is a key inflammatory cytokine that plays a critical role in tissue inflammation and autoimmune diseases. However, its signaling remains poorly understood. In this study, we identified serine/threonine kinase 24 (Stk24) as a positive modulator of IL-17-mediated signaling and i...

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Vydáno v:Front Immunol
Hlavní autoři: Jiang, Yu, Tian, Miao, Lin, Wenlong, Wang, Xinyuan, Wang, Xiaojian
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936754/
https://ncbi.nlm.nih.gov/pubmed/29760709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00921
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