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How to deal with the Poisson-gamma model to forecast patients' recruitment in clinical trials when there are pauses in recruitment dynamic?

Recruiting patients is a crucial step of a clinical trial. Estimation of the trial duration is a question of paramount interest. Most techniques are based on deterministic models and various ad hoc methods neglecting the variability in the recruitment process. To overpass this difficulty the so-call...

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Библиографические подробности
Опубликовано в: :Contemp Clin Trials Commun
Главные авторы: Minois, Nathan, Savy, Stéphanie, Lauwers-Cances, Valérie, Andrieu, Sandrine, Savy, Nicolas
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936707/
https://ncbi.nlm.nih.gov/pubmed/29740630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2017.01.003
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