Effective preparation of a monoclonal antibody against human chromogranin A for immunohistochemical diagnosis

BACKGROUND: Human chromogranin A (CgA) is a ~ 49 kDa secreted protein mainly from neuroendocrine cells and endocrine cells. The CgA values in the diagnosis of tumor, and in the potential role in prognostic and predictive tumor as a biomarker. RESULTS: The synthesized gene of CgA coding area was clon...

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Veröffentlicht in:BMC Biotechnol
Hauptverfasser: Zhang, Danping, Xie, Chengjie, Wang, Rongzhi, Yang, Qinghai, Chen, Huiling, Ling, Sumei, Wang, Shihua, Jia, Kunzhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935939/
https://ncbi.nlm.nih.gov/pubmed/29728076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-018-0436-z
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