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Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin—resistant Staphylococcus aureus

The emergence of Staphylococcus aureus strains resistant to ‘last resort’ antibiotics compels the development of new antimicrobials against this important human pathogen. We found that propyl 5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC) shows bacteriostatic activity against S. aur...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Johnston, Tatiana, Van Tyne, Daria, Chen, Roy F., Fawzi, Nicolas L., Kwon, Bumsup, Kelso, Michael J., Gilmore, Michael S., Mylonakis, Eleftherios
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935714/
https://ncbi.nlm.nih.gov/pubmed/29728636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25571-w
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