Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB

Pore-forming toxins (PFT) are virulence factors that transform from soluble to membrane-bound states. The Yersinia YaxAB system represents a family of binary α-PFTs with orthologues in human, insect, and plant pathogens, with unknown structures. YaxAB was shown to be cytotoxic and likely involved in...

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Publicat a:Nat Commun
Autors principals: Bräuning, Bastian, Bertosin, Eva, Praetorius, Florian, Ihling, Christian, Schatt, Alexandra, Adler, Agnes, Richter, Klaus, Sinz, Andrea, Dietz, Hendrik, Groll, Michael
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935710/
https://ncbi.nlm.nih.gov/pubmed/29728606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04139-2
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