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The Biology of Monoclonal Antibodies: Focus on Calcitonin Gene-Related Peptide for Prophylactic Migraine Therapy

Calcitonin gene-related peptide (CGRP) is 37-amino-acid neuropeptide, crucially involved in migraine pathophysiology. Four monoclonal antibodies (mAbs) targeting the CGRP pathway are currently under evaluation for the prevention of episodic and chronic migraine: eptinezumab (ALD403), fremanezumab (T...

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Publicat a:Neurotherapeutics
Autors principals: Raffaelli, Bianca, Reuter, Uwe
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935651/
https://ncbi.nlm.nih.gov/pubmed/29616494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-0622-7
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