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Targeted CGRP Small Molecule Antagonists for Acute Migraine Therapy

Migraine is a highly prevalent, severe, and disabling neurological condition with a significant unmet need for effective acute therapies. Patients (~50%) are dissatisfied with their currently available therapies. Calcitonin gene-related peptide (CGRP) has emerged as a key neuropeptide involved in th...

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Bibliographic Details
Published in:Neurotherapeutics
Main Authors: Holland, Philip R., Goadsby, Peter J.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935646/
https://ncbi.nlm.nih.gov/pubmed/29556965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-0617-4
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