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Phase transitions in the assembly and function of human miRISC

miRISC is a multi-protein assembly that uses microRNAs (miRNAs) to identify mRNAs targeted for repression. Dozens of miRISC-associated proteins have been identified and interactions between many factors have been examined in detail. However, the physical nature of the complex remains unknown. Here,...

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Publicat a:Cell
Autors principals: Sheu-Gruttadauria, Jessica, MacRae, Ian J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935535/
https://ncbi.nlm.nih.gov/pubmed/29576456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.02.051
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