Colorectal tumors require NUAK1 for protection from oxidative stress

Exploiting oxidative stress has recently emerged as a plausible strategy for treatment of human Cancer and anti-oxidant defences are implicated in resistance to chemo- and radiotherapy. Targeted suppression of anti-oxidant defences could thus broadly improve therapeutic outcomes. Here we identify th...

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Bibliografiska uppgifter
I publikationen:Cancer Discov
Huvudupphovsmän: Port, Jennifer, Muthalagu, Nathiya, Raja, Meera, Ceteci, Fatih, Monteverde, Tiziana, Kruspig, Bjorn, Hedley, Ann, Kalna, Gabriela, Lilla, Sergio, Neilson, Lisa, Brucoli, Martina, Gyuraszova, Katarina, Tait-Mulder, Jacqueline, Mezna, Mokdad, Svambaryte, Silvija, Bryson, Amy, Sumpton, David, McVie, Allan, Nixon, Colin, Drysdale, Martin, Esumi, Hiroyasu, Murray, Graeme I., Sansom, Owen J., Zanivan, Sara R., Murphy, Daniel J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935231/
https://ncbi.nlm.nih.gov/pubmed/29500295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0533
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