Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions

BACKGROUND: The phosphatase chronophin (CIN/PDXP) has been shown to be an important regulator of glioma cell migration and invasion. It has two known substrates: p-Ser3-cofilin, the phosphorylated form of the actin binding protein cofilin, and pyridoxal 5′-phosphate, the active form of vitamin B6. P...

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Dettagli Bibliografici
Pubblicato in:BMC Cancer
Autori principali: Schulze, Markus, Hutterer, Maria, Sabo, Anja, Hoja, Sabine, Lorenz, Julia, Rothhammer-Hampl, Tanja, Herold-Mende, Christel, Floßbach, Lucia, Monoranu, Camelia, Riemenschneider, Markus J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934884/
https://ncbi.nlm.nih.gov/pubmed/29724193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4440-4
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