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Surrogate potency assays: Comparison of binding profiles complements dose response curves for unambiguous assessment of relative potencies

Surface plasmon resonance (SPR) systems are widely used for detailed characterization of antibody activities including antigen and Fc-receptor binding. During the later stages of development, where the focus is to ensure that established critical quality attributes (CQAs) are maintained during cell...

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Bibliografiska uppgifter
I publikationen:J Pharm Anal
Huvudupphovsmän: Karlsson, Robert, Fridh, Veronica, Frostell, Åsa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Xi'an Jiaotong University 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934736/
https://ncbi.nlm.nih.gov/pubmed/29736301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2017.12.008
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