Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide–gated and ryanodine 2 channels

BACKGROUND: Aging is associated with an increased incidence of atrioventricular nodal (AVN) dysfunction. OBJECTIVE: The aim of this study was to investigate the structural and functional remodeling in the atrioventricular junction (AVJ) with aging. METHODS: Electrophysiology, histology, and immunohi...

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Bibliographic Details
Published in:Heart Rhythm
Main Authors: Saeed, Yawer, Temple, Ian P., Borbas, Zoltan, Atkinson, Andrew, Yanni, Joseph, Maczewski, Michal, Mackiewicz, Urszula, Aly, Mariam, Logantha, Sunil Jit R.J., Garratt, Clifford J., Dobrzynski, Halina
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934612/
https://ncbi.nlm.nih.gov/pubmed/29288034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2017.12.027
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