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MiR-182 promotes cell proliferation by suppressing FBXW7 and FBXW11 in non-small cell lung cancer

Objective: MicroRNAs have been found to be deregulated in lung cancers, which play crucial roles in tumorigenesis and progression. FBXW7 and FBXW11, two important F-box proteins of the ubiquitin-proteasome system (UPS), can target multiple substrates for degradation, in order to regulate cell prolif...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Chang, Hao, Liu, Yue-Hong, Wang, Li-Li, Wang, Ju, Zhao, Zhi-Hong, Qu, Jun-Feng, Wang, Sheng-Fa
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934572/
https://ncbi.nlm.nih.gov/pubmed/29736206
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