Lysophosphatidylcholine Promotes Phagosome Maturation and Regulates Inflammatory Mediator Production Through the Protein Kinase A–Phosphatidylinositol 3 Kinase–p38 Mitogen-Activated Protein Kinase Signaling Pathway During Mycobacterium tuberculosis Infection in Mouse Macrophages

Tuberculosis is caused by the infectious agent Mycobacterium tuberculosis (Mtb). Mtb has various survival strategies, including blockade of phagosome maturation and inhibition of antigen presentation. Lysophosphatidylcholine (LPC) is a major phospholipid component of oxidized low-density lipoprotein...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lee, Hyo-Ji, Ko, Hyun-Jeong, Song, Dong-Kun, Jung, Yu-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934435/
https://ncbi.nlm.nih.gov/pubmed/29755479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00920
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