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Determination of Minimal Steady-State Plasma Level of Diazepam Causing Seizure Threshold Elevation in Rats

OBJECTIVE: Diazepam, administered by the intravenous, oral or rectal routes, is widely used for the management of acute seizures. Dosage forms for delivery of diazepam by other routes of administration, including intranasal, intramuscular and transbuccal, are under investigation. In predicting what...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Dhir, Ashish, Rogawski, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934328/
https://ncbi.nlm.nih.gov/pubmed/29682729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14069
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