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Insulin‐producing cells derived from ‘induced pluripotent stem cells’ of patients with fulminant type 1 diabetes: Vulnerability to cytokine insults and increased expression of apoptosis‐related genes

AIMS/INTRODUCTION: The present study was carried out to generate induced pluripotent stem cells (iPSCs) from patients with fulminant type 1 diabetes, and evaluate the cytokine‐induced apoptotic reactions of β‐like insulin‐producing cells differentiated from the iPSCs. MATERIALS AND METHODS: iPSCs we...

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Detalhes bibliográficos
Publicado no:J Diabetes Investig
Main Authors: Hosokawa, Yoshiya, Toyoda, Taro, Fukui, Kenji, Baden, Megu Yamaguchi, Funato, Michinori, Kondo, Yasushi, Sudo, Tomomi, Iwahashi, Hiromi, Kishida, Marina, Okada, Chihiro, Watanabe, Akira, Asaka, Isao, Osafune, Kenji, Imagawa, Akihisa, Shimomura, Iichiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934265/
https://ncbi.nlm.nih.gov/pubmed/28796422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12727
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