Designing Tyrosinase siRNAs by Multiple Prediction Algorithms and Evaluation of Their Anti-Melanogenic Effects

Melanin is a pigment produced from tyrosine in melanocytes. Although melanin has a protective role against UVB radiation-induced damage, it is also associated with the development of melanoma and darker skin tone. Tyrosinase is a key enzyme in melanin synthesis, which regulates the rate-limiting ste...

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Bibliografiske detaljer
Udgivet i:Biomol Ther (Seoul)
Main Authors: Kwon, Ok-Seon, Kwon, Soo-Jung, Kim, Jin Sang, Lee, Gunbong, Maeng, Han-Joo, Lee, Jeongmi, Hwang, Gwi Seo, Cha, Hyuk-Jin, Chun, Kwang-Hoon
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Society of Applied Pharmacology 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933895/
https://ncbi.nlm.nih.gov/pubmed/29223142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2017.115
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