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Dexmedetomidine inhibits inflammatory reaction in the hippocampus of septic rats by suppressing NF-κB pathway

Dexmedetomidine (DEX) is known to provide neuroprotective effect in the central nervous system. However, the detailed mechanism remains far more elusive. This study was designed to investigate the relevant mechanisms of DEX's neuroprotective effect. Sprague–Dawley (SD) rats were injected with d...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Zhang, Xiaobao, Yan, Fang, Feng, Jiying, Qian, Haitao, Cheng, Zhi, Yang, Qianqian, Wu, Yong, Zhao, Zhibin, Li, Aimin, Xiao, Hang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933780/
https://ncbi.nlm.nih.gov/pubmed/29723264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196897
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