Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation

BACKGROUND: Type 1 and Type 2 diabetes mellitus (T1DM and T2DM) are caused by beta(β)-cell loss and functional impairment. Identification of mechanisms of β-cell death and therapeutic interventions to enhance β-cell survival are essential for prevention and treatment of diabetes. Oxidative stress is...

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Publicado en:PLoS One
Main Authors: Miki, Atsushi, Ricordi, Camillo, Sakuma, Yasunaru, Yamamoto, Toshiyuki, Misawa, Ryosuke, Mita, Atsuyoshi, Molano, Ruth D., Vaziri, Nosratola D., Pileggi, Antonello, Ichii, Hirohito
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933778/
https://ncbi.nlm.nih.gov/pubmed/29723228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196570
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